\documentclass{presentation}

\title{Development of \\ Frequency Domain Multidimensional Spectroscopy}
\author{Blaise Thompson}

\institute{University of Wisconsin--Madison}
\date{2018-04-23}
%\subject{}

\begin{document}
\maketitle

\section{CMDS}  % =================================================================================

\begin{frame}{CMDS}
	The Wright Group focuses on the development and usage of \\
  Coherent MultiDimensional Spectroscopy (CMDS).
  \vspace{\baselineskip} \\
  CMDS is a family of related nonlinear spectroscopic experiments.
\end{frame}
   
\begin{frame}{Why CMDS?}
  [A BUNCH OF COOL PUBLICATIONS---FOCUSING ON COHERENCE TRANSFER, MECHANISMS ETC]
  [MORE APPLICATIONS]
\end{frame}

\begin{frame}{Coherence transfer}
  \fbox{\adjincludegraphics[width=\textwidth]{literature/ChenuAurelia2014a}}
\end{frame}

\begin{frame}{Analytical}
  But wait! I'm an \emph{Analytical} Chemist...
  \vspace{\baselineskip} \\
  What am I doing in a field so rich with fundamental studies?
  \vspace{\baselineskip} \\
  I hope to convince you that CMDS can be used for analytical work.  % TODO: better
\end{frame}

% TODO: in fact, 2DIR is already used regularly...

\begin{frame}{Analytical}  
  \fbox{\adjincludegraphics[width=\textwidth]{literature/PakoulevAndreiV2009a}}
\end{frame}

% TODO: pakoulev quotes

\begin{frame}{Proteomics}
  \fbox{\adjincludegraphics[width=\textwidth]{literature/FournierFrederic2009a}}
\end{frame}

% TODO: fournier quotes

\begin{frame}{Proteomics}
  \fbox{\adjincludegraphics[width=\textwidth]{literature/DonaldsonPaulMurray2010a}}
\end{frame}

% TODO: donaldson quotes
  
\section{Frequency domain}  % =====================================================================

\begin{frame}{Domains of CMDS}
  CMDS can be collected in two domains:
  \begin{itemize}
    \item time domain
    \item frequency domain
  \end{itemize}
\end{frame}

\begin{frame}{Time domain}
  Multiple broadband pulses are scanned in \emph{time} to collect a multidimensional interferogram.
  \vspace{\baselineskip} \\
  A local oscillator must be used to measure the \emph{phase} of the output.
  \vspace{\baselineskip} \\
  This technique is...
  \begin{itemize}
    \item fast (even single shot)
    \item robust
  \end{itemize}
  pulse shapers have made time-domain CMDS (2DIR) almost routine.
\end{frame}

\begin{frame}{Frequency domain}
  In the Wright Group, we focus on \emph{frequency} domain ``Multi-Resonant'' (MR)-CMDS.
  \vspace{\baselineskip} \\
  Automated Optical Parametric Amplifiers (OPAs) are used to produce relatively narrow-band pulses.
  Multidimensional spectra are collected ``directly'' by scanning OPAs against each-other.
  \vspace{\baselineskip} \\
  This strategy is...
  \begin{itemize}
    \item slow (must directly visit each pixel)
    \item fragile (many crucial moving pieces)
  \end{itemize}
  but! It is incredibly flexible.  
\end{frame}

\begin{frame}{Bandwidth}
  MR-CMDS has no bandwidth limit!
  \vspace{\baselineskip} \\
  There is just the small matter of making the source continuously tunable...
  \adjincludegraphics[width=\textwidth]{opa/OPA_ranges}
\end{frame}

\begin{frame}{Selection rules}
  MR-CMDS can easily collect data without an external local oscillator.
  \vspace{\baselineskip} \\
  This means... [BOYLE]
\end{frame}

\section{The instrument}  % =======================================================================

\begin{frame}{The instrument}
  [PICTURE OF LASER LAB]
\end{frame}

\begin{frame}{The instrument}
  Many kinds of component hardware
  \begin{itemize}
    \item monochromators
    \item delay stages
    \item filters
    \item OPAs
  \end{itemize}
  $\sim10$ settable devices, $\sim25$ motors. \\
  Multiple detectors.
\end{frame}

\begin{frame}{Pipeline}
  \adjincludegraphics[width=0.5\textwidth]{presentation/pipe}
  What does the ``pipeline'' of MR-CMDS data acquisition and processing look like in the Wright
  Group?
  \vspace{\baselineskip} \\
  How to increase data throughput and quality, while decreasing frustration of experimentalists?  %
\end{frame}

\section{Processing}  % ===========================================================================

\begin{frame}{Processing}
  WrightTools.
\end{frame}

\begin{frame}{Universal format}
\end{frame}

\begin{frame}{Flexible data model}
\end{frame}

\section{Acquisition}  % ==========================================================================

\begin{frame}{Acquisition}
  PyCMDS.
\end{frame}

\begin{frame}{Modular hardware model}
\end{frame}

\begin{frame}{Acquisitions}
\end{frame}

\begin{frame}{Queue}
  This strategy can be incredibly productive!
  \begin{itemize}
    \item Soon after the queue was first implemented, we collected more pixels in two weeks than
      had been collected over the previous three years.
  \end{itemize}
\end{frame}

\section{Tuning}  % ===============================================================================

\begin{frame}{Tuning}
\end{frame}

\section{Supplement}  % ===========================================================================

\begin{frame}{MR-CMDS theory}
\end{frame}

\begin{frame}{Mixed domain}
  [FIGURES FROM DAN'S PAPER]
\end{frame}

\end{document}